Global health review
A weekly round-up of all the latest global health research from MSF projects and beyond
13 September 2024
Registration for the MSF Scientific Days – Asia 2024 conference on 25 October is now open! This year, MSF collaborates with Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital to present research, innovation, and experiences from humanitarian programmes across Asia.
eClinicalMedicine warns that infants born to mothers with multidrug-resistant or rifampicin-resistant tuberculosis (TB) are at a higher risk of developing TB if the mother's adherence to treatment or antiretroviral therapy is suboptimal. The same journal finds migrants in Europe are at higher risk of acquiring resistant bacteria, particularly gram-negative bacteria, within community settings such as refugee camps and detention centres.
The Lancet Global Health assesses a hospital intervention aimed at enhancing medical oxygen services for neonates and children in Uganda. PLOS Global Public Health identifies heat waves as a risk factor for diarrhoea hospitalisation in Dhaka, Bangladesh, particularly during the pre-monsoon summer season. The team finds a 7% increase in diarrhoea hospitalisations for all ages but a 14% increase among children under 5 years of age. Finally, The BMJ highlights the various impacts experienced by children in conflict zones and urges for a renewed global commitment to the distinct needs and rights of children in crisis.
Best regards,
Lydia Lampiri, Zhi Wei Ching, Ononna Thuli and Holly Baker with MSF-authored article assistance from Patricia Kahn and Amelia Zhao.
All MSF-authored publications can be found on the MSF Science Portal, as well as recordings, abstracts and posters from the MSF Scientific Days 2024 conference.
Antimicrobial resistance
eClinicalMedicine • Article: Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis – update from 2017 to 2023
The Lancet Global Health • Article: Microbiology testing capacity and antimicrobial drug resistance in surgical-site infections: a post-hoc, prospective, secondary analysis of the FALCON randomised trial in seven low-income and middle-income countries
Climate change and Planetary Health
PLOS Global Public Health • Article: Is heat wave a predictor of diarrhoea in Dhaka, Bangladesh? A time-series analysis in a South Asian tropical monsoon climate
Conflict, migration and health
BMJ • News***MENTIONS MSF***: MSF opens field hospital in Gaza
BMJ • Analysis: When is enough, enough? Humanitarian rights and protection for children in conflict settings must be revisited
Ebola
The Lancet Microbe • Article: Fatal meningoencephalitis associated with Ebola virus persistence in two survivors of Ebola virus disease in the Democratic Republic of the Congo: a case report study
Global health
BMJ • News: Cholera: Marked increase in cases and deaths globally, data show
The Lancet Global Health • Article: Cost-effectiveness and health impact of screening and treatment of Mycobacterium tuberculosis infection among formerly incarcerated individuals in Brazil: a Markov modelling study
PLOS Global Public Health • Article: Perspectives on health, illness, disease and management approaches among Baganda traditional spiritual healers in Central Uganda
BMJ • Letter: Public engagement in defining triage before future pandemics
The Lancet Planetary Health • Article: Risks of infectious disease hospitalisations in the aftermath of tropical cyclones: a multi-country time-series study
The Lancet Global Health • Article: The costs and benefits of scaling up interventions to prevent poor birth outcomes in low-income and middle-income countries: a modelling study
BMJ Global Health • Article: The global health and economic value of COVID-19 vaccination
BMJ • other: Underfunding public health has wide ranging consequences
WHO Bulletin • Practice: WHO and improved global standards for medical products of human origin
WHO Bulletin • Practice: WHO Model list of essential medicines: visions for the future
HIV
The Lancet HIV • Article: Bacterial sexually transmitted infections among men who have sex with men and transgender women using oral pre-exposure prophylaxis in Latin America (ImPrEP): a secondary analysis of a prospective, open-label, multicentre study
PLOS Global Public Health • Article: Correlates of HIV treatment adherence self-efficacy among adolescents and young adults living with HIV in southwestern Uganda
PLOS Global Public Health • Article: Do HIV provider and client perspectives align on person-centered care? Lessons learned from implementation of the Person-Centered Care Assessment Tool (PCC-AT) in HIV treatment settings in Ghana
eBioMedicine • Article: Immune correlates analysis of the Imbokodo (HVTN 705/HPX2008) efficacy trial of a mosaic HIV-1 vaccine regimen evaluated in Southern African people assigned female sex at birth: a two-phase case-control study
PLOS Global Public Health • Article: Influence of the SARS-COV2 pandemic on access to healthcare services among people living with HIV and its subsequent effects on antiretroviral therapy uptake in Malawi
The Lancet HIV • Article: Real-world effectiveness and tolerability of switching to doravirine-based antiretroviral therapy in people with HIV: a nationwide, matched, prospective cohort study
The Lancet Global Health • Article: The effect on HIV transmission and cost-effectiveness of programmes for female sex workers in East, Central, and Southern Africa: a modelling study
PLOS Global Public Health • Article: The fall—And rise—In hospital-based care for people with HIV in South Africa: 2004–2017
Malaria
Malaria Journal • Article: Antimalarial drug sulfadoxine induces gametocytogenesis in Plasmodium berghei
Malaria Journal • Article: Asymptomatic carriage of Plasmodium falciparum in children living in a hyperendemic area occurs independently of IgG responses but is associated with a balanced inflammatory cytokine ratio
The Lancet Global Health • Article: Community-based strategies to increase coverage of intermittent preventive treatment of malaria in pregnancy with sulfadoxine–pyrimethamine in sub-Saharan Africa: a systematic review, meta-analysis, meta-ethnography, and economic assessment
Malaria Journal • Article: Knowledge, attitude and practice levels regarding malaria among the Semai sub-ethnic indigenous Orang Asli communities in Pahang, Peninsular Malaysia: a stepping stone towards the prevention of human malaria re-establishment
PLOS Global Public Health • Article: Multilevel predictors of anaemia among pregnant women in Ghana: New evidence from the 2019 Ghana Malaria Indicator Survey
Malaria Journal • Article: Perceived barriers and opportunities for the introduction of post-discharge malaria chemoprevention (PDMC) in five sub-Saharan countries: a qualitative survey amongst malaria key stakeholders
BMJ Global Health • Article: The effects of climatic and non-climatic factors on malaria mortality at different spatial scales in western Kenya, 2008–2019
Maternal and child health
PLOS Medicine • Article: A comprehensive assessment of care competence and maternal experience of first antenatal care visits in Mexico: Insights from the baseline survey of an observational cohort study
PLOS Global Public Health • Article: Anaemia at 36 weeks of pregnancy: Prevalence and determinants among antenatal women attending peri-urban facilities in a developing country, Ghana
PLOS Global Public Health • Article: Barriers and facilitators for implementing the WHO Safe Childbirth Checklist (SCC) in Mozambique: A qualitative study using the Consolidated Framework for Implementation Research (CFIR)
WHO Bulletin • Other: Building sustainable capacity to adopt, adapt or develop child health guidelines, Malawi, Nigeria and South Africa
PLOS Global Public Health • Article: Capacity for delivery of paediatric emergency care and the current use of emergency triage, assessment and treatment in health facilities in the Busoga region, Uganda—A mixed methods study
eClinicalMedicine • Article: Critical assessment of infants born to mothers with drug resistant tuberculosis
PLOS Global Public Health • Article: Determinants of dropout from the maternal continuum of care in Ethiopia, multilevel analysis of the 2016 demographic and health survey
Tropical Medicine & International Health • Article: Development of a health literacy scale for COVID-19 prevention among pregnant women in Thailand
PLOS Global Public Health • Article: Factors associated with knowledge and practices of COVID-19 prevention among mothers of under-2 children in Bangladesh
PLOS Global Public Health • Article: Factors influencing the maternal choice of packaged snacks for 6–10 years old children: A cross-sectional study from Sri Lanka
RSTMH Transactions • Article: Foetal outcome of Leptospira and Rickettsial infections during pregnancy: a systematic reviewGet access
The Lancet Global Health • Article: Improving effective coverage of medical-oxygen services for neonates and children in health facilities in Uganda: a before–after intervention study
JAMA Network Open • Article: Neurological Symptoms and Cause of Death Among Young Children in Low- and Middle-Income Countries
PLOS Global Public Health • Article: Predicting blood lead in uruguayan children: Individual- vs neighborhood-level ensemble learners
PLOS Global Public Health • Article: Unveiling the significance of women’s role in health-seeking behavior during suspected malaria fever in risk populations of Nepal: Mixed methods cross-sectional study
Mental health
Tropical Medicine & International Health • Article: Association between experienced stigma, anxiety, depression and loneliness among people with drug‐resistant tuberculosis in Lagos Nigeria: The moderating role of social support
Neglected tropical diseases
Tropical Medicine & International Health • Article: A case–control study on risk factors for visceral leishmaniasis in West Pokot County, Kenya
PLOS NTDs • Article: A novel antigen biomarker for detection of high-level of Loa loa microfilaremia
PLOS NTDs • Article: AcuM and AcuK: The global regulators controlling multiple cellular metabolisms in a dimorphic fungus Talaromyces marneffei
PLOS NTDs • Article: Analysis of Cholera Risk in India: Insights from 2017–18 Serosurvey Data Integrated with Epidemiologic data and Societal Determinants from 2015–2019
PLOS NTDs • Article: Antibodies against medically relevant arthropod-borne viruses in the ubiquitous African rodent Mastomys natalensis
PLOS NTDs • Article: Changing seroprevalence of schistosomiasis japonica in China from 1982 to 2020: A systematic review and spatial analysis
BMJ • Feature: Dementia: Africa’s unique opportunity for prevention amid rising cases
PLOS NTDs • Article: Diagnosis of brucellosis: Combining tests to improve performance
PLOS NTDs • Article: Epigenetic Biomarkers and the Wnt/β-Catenin Pathway in Opisthorchis viverrini-associated Cholangiocarcinoma: A Scoping Review on Therapeutic Opportunities
PLOS NTDs • Article: Expression of Concern: Protective Role of Acetylsalicylic Acid in Experimental Trypanosoma cruzi Infection: Evidence of a 15-epi-Lipoxin A4-Mediated Effect
PLOS NTDs • Article: Genomic analysis of Strongyloides stercoralis and Strongyloides fuelleborni in Bangladesh
PLOS NTDs • Viewpoint: Hope amidst neglect: Mycetoma Research Center, University of Khartoum. A holistic management approach to achieve the United Nations’ Sustainable Development Goals
PLOS NTDs • Article: Impact of vaccination against Japanese encephalitis in endemic countries
PLOS NTDs • Article: Isolation and characterization of genetic variants of Orthohantavirus hantanense from clinical cases of HFRS in Jiangxi Province, China
PLOS NTDs • Article: Linked-evidence modelling of qualitative G6PD testing to inform low- and intermediate-dose primaquine treatment for radical cure of Plasmodium vivax
PLOS NTDs • Article: Neglected tropical disease meets neglected community: Street children’s susceptibility to scabies in Addis Ababa, Ethiopia
PLOS NTDs • Article: Paracoccidioides lutzii Infects Galleria mellonella Employing Formamidase as a Virulence Factor
The Lancet Regional Health – Europe • Article: Prevalence of Chagas disease among Latin American immigrants in non-endemic countries: an updated systematic review and meta-analysis
PLOS NTDs • Article: Prevalence of onchocerciasis and epilepsy in a Tanzanian region after a prolonged community-directed treatment with ivermectin
PLOS NTDs • Article: Prevention of congenital chagas disease by trypanocide treatment in women of reproductive age: A meta-analysis of observational studies
The Lancet Infectious Diseases • Article: Safety and immunogenicity of a live-attenuated chikungunya virus vaccine in endemic areas of Brazil: interim results of a double-blind, randomised, placebo-controlled phase 3 trial in adolescents
PLOS NTDs • Article: The impact of modified incision height and surgical procedure on trichiasis surgery outcomes: Results of the maximizing trichiasis surgery success (MTSS) randomized trial
Non-communicable diseases
PLOS Global Public Health • Article: “The peace that I wanted, I got”: Qualitative insights from patient experiences of SMART DAPPER interventions for major depression and traumatic stress disorders in Kenya
RSTMH Transactions • Article: A combined tropical medicine and psychiatry approach to patients with possible delusional infestation
PLOS Global Public Health • Article: A mediation analysis evaluating change in self-stigma on diabetes outcomes among people with depression in urban India: A secondary analysis from the INDEPENDENT trial of the collaborative care model
PLOS Global Public Health • Article: Assessing compliance with national guidelines in diabetes care: A study leveraging data from south Africa’s National Health Laboratory Service (NHLS)
The Lancet Regional Health – Western Pacific • Article: Burden of cardiovascular disease among the Western Pacific region and its association with human resources for health, 1990–2021: a systematic analysis of the Global Burden of Disease Study 2021
PLOS Global Public Health • Article: Gestational weight gain at the national, regional, and income group levels based on 234 national household surveys from 70 low-income and middle-income countries
PLOS Global Public Health • Article: Global consumption patterns of combination hypertension medication: An analysis of pharmaceutical sales data from 2010–2021
eClinicalMedicine • Article: Global, regional, and national burden of tracheal, bronchus, and lung cancer and its risk factors from 1990 to 2021: findings from the global burden of disease study 2021
PLOS Global Public Health • Article: Improving childhood cancer medicines access in developing countries: Towards an implementation framework to inform the Global Platform for Access to Childhood Cancer Medicines for Nigeria
The Lancet Regional Health – Western Pacific • Article: Readmission destination following cardiac surgery and its association with mortality outcomes: a population-based retrospective study
The Lancet Global Health • Article: The global macroeconomic burden of Alzheimer's disease and other dementias: estimates and projections for 152 countries or territories
Outbreaks
PLOS Global Public Health • Article: The impacts of COVID-19 on older adults in Uganda and Ethiopia: Perspectives from non-governmental organization staff and volunteers
BMJ • News: Why are doctors being warned about the Oropouche virus?
Research and reporting
The Lancet Regional Health – Western Pacific • Article: Acceptability of a nationwide scabies mass drug administration (MDA) program in Fiji: a qualitative interview-based study
BMJ Global Health • Article: Adolescent and youth-friendly health interventions in low-income and middle-income countries: a scoping review
The Lancet Global Health • Article: Assessing the prevalence and impact of preserved ratio impaired spirometry in low-income and middle-income countries: a post-hoc cross-sectional analysis
BMJ Global Health • Practice: Effective community entry: reflections on community engagement in culturally sensitive research in southwestern Nigeria
The Lancet Gastroenterology & Hepatology • Article: Global prevalence and characteristics of infections and clinical outcomes in hospitalised patients with cirrhosis: a prospective cohort study for the CLEARED Consortium
BMJ Global Health • Comment: Integrating social behavioural insights in risk communication and community engagement approaches for better health outcomes in Africa
The Lancet Global Health • Article: Mechanisms and causes of death after abdominal surgery in low-income and middle-income countries: a secondary analysis of the FALCON trial
PLOS Global Public Health • Article: Water fetching and musculoskeletal health across the life-course in Sub-Saharan Africa: A scoping review
Sexual and reproductive health
PLOS Global Public Health • Article: Factors associated with the ability of adolescent girls and young women (AGYW) in sexual unions to negotiate for safer sex. An analysis of data from the 2018 Zambia Demographic and Health Survey (ZDHS)
Tuberculosis
PLOS Global Public Health • Article: Leveraging tuberculosis programs for future pandemic preparedness: A retrospective look on COVID-19
PLOS Global Public Health • Article: Post-tuberculosis lung disease: Addressing the policy gap
Vaccines
The Lancet Global Health • Article: Effectiveness and impact of monovalent rotavirus vaccination in Afghanistan: a test-negative case–control analysis
WHO Bulletin • Other: Increasing immunization coverage, Solomon Islands, 2022
The Lancet Global Health • Article: Long-term effect of pneumococcal conjugate vaccines on invasive pneumococcal disease incidence among people of all ages from national, active, laboratory-based surveillance in South Africa, 2005–19: a cohort observational study
The Lancet Global Health • Article: Re-evaluating the impact and cost-effectiveness of pneumococcal conjugate vaccine introduction in 112 low-income and middle-income countries in children younger than 5 years: a modelling study